Search on: HISTIDINE KINASE 
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Descriptor English:   Histidine Kinase 
Descriptor Spanish:   Histidina Quinasa 
Descriptor Portuguese:   Histidina Quinase 
Synonyms English:   Histidine Protein Kinase
Histone H4 Histidine Kinase
Protein Histidine Pros-Kinase
Protein-Histidine Kinase
Protein-Histidine Tele-Kinase
Sensor Histidine Kinase
Histidine Kinase, Sensor
Histidine Pros-Kinase, Protein
Kinase, Histidine
Kinase, Histidine Protein
Kinase, Protein-Histidine
Kinase, Sensor Histidine
Pros-Kinase, Protein Histidine
Protein Histidine Kinase
Protein Histidine Pros Kinase
Protein Histidine Tele Kinase
Protein Kinase, Histidine
Tele-Kinase, Protein-Histidine  
Tree Number:   D08.811.913.696.620.682.675
Definition English:   A member of the transferase superfamily of proteins. In the activated state, protein-histidine kinase autophosphorylates at a histidine residue, subsequently transferring high-energy phosphoryl groups to an aspartate residue of the response-regulator domain, which results in a conformational shift in the effector domain. Histidine kinases mediate signal transduction in a wide range of processes involving cellular adaptation to environmental stress. 
History Note English:   2017 (1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56508 
Unique Identifier:   D000071677 

Occurrence in VHL: 		 

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